Population health management (PHM) is a hot topic in the healthcare industry, but it means many different things to different people in different contexts. Deciding where to focus effort when developing PHM strategies and programmes is difficult without a clear policy framework and approach. Milliman consultants have written a guide to help managers think through the practical components of a PHM programme, from overall objectives and definitions through to the people. The guide also explores processes and technology enablers that are critical for success. Real-world case studies are referenced to demonstrate how the concepts discussed in the guide can be applied.